Elaine Grey is the mother of founding X-Men member, Jean Grey and the wife of John Grey.
During the Inferno storyline, Elaine and her husband were temporarily transformed into a demon by the Goblyn Queen, a clone of their daughter, Jean.
After the death of her daughter, Sara Grey-Bailey, and possibly her husband Paul, Dr. Grey and his wife Elaine took care of their grandchildren, Gailyn and Joey.
When Operation: Zero Tolerance occurred, John was aided by Nate Grey, who ironically is an alternate version of his grandson, Nathan Summers, in saving his grandchildren, Joey & Gailyn.
Elaine was the last member of the Grey family to be killed by the Shi'ar Death Commandos having survived the initial attack. She was protected by both Rachel and Psylocke and watched the deaths of all her family. She denounced Rachel Grey as being her granddaughter and wished that her daughter Jean Grey had never been born, before dying from an optic blast from Black Cloak that was meant for Rachel.