Psyklop is a member of an intelligent insectoid-humanoid race which evolved from insects and existed on Earth and dominated the planet in prehistoric times; during their time, Psyklop's race prospered, but they soon fell out of favor with their Dark Gods they worshipped, and were put into a state of hibernation by them. 
Eons later, Psyklop is awakened by the Dark Gods, who charge him with the responsibility of finding a power source for them, and he did so, his race would be awakened and allowed to conquer the Earth. After covertly creating a voodoo-based cult in New Orleans, Psyklop discovers that the Hulk possessed the power he needs to energize the Dark Gods. Transporting the Hulk to his lair, Psyklop, explaining his origin and intentions to him, begins the process of shrinking the Hulk to a size where his molecular structure can be examined better. Unfortunately, Psyklop loses track of the Hulk when he is distracted by the Avengers, who have traced Psyklop to his base. Battling the Avengers, Psyklop manages to blast them with a device that erases their memories and teleports them to a subway platform in New York.
Afterwards, Psyklop, after searching for the Hulk, finds him in the sub-atomic world of K'ai. Still wanting to harness the power of the Hulk, Psyklop shrinks himself to capture him. Successfully obtaining the Hulk, Psyklop returns to his base with him, only to be violently pummeled by the Hulk. As the Hulk prepares to kill Psyklop, Psyklop himself is quickly taken away by the Dark Gods, who have decided to abandon him as their agent. It is later revealed that Psyklop has been simply dumped on K'ai by the Dark Gods and was left with no way to return to his regular size.
While on K'ai, Psyklop begins to form a plan, inspired by an incident caused by the Hulk, who had accidentally kicked K'ai while leaving the planet, causing chaotic earthquakes. Creating a large drilling device, Psyklop begins to create catastrophic earthquakes on K'ai, telling the planet's inhabitants he would only stop his destruction if they worshipped him as a God; Psyklop also captures the spirits of those who died in his earthquakes, planning on giving the spirits to the Dark Gods as a power source, wanting to regain their favor. The Hulk, wanting to face this "angry God" who threatened the inhabitants of K'ai, ventures to Psyklop's headquarters with Jarella to confront the God. After destroying a robotic sentinel at Psyklop's base, the Hulk is knocked unconscious by Psyklop, who blasts him with a large projectile weapon.
Restraining the Hulk, Psyklop begins to taunt Jarella, only for the Hulk to escape. Having all his weaponry destroyed by the Hulk, Psyklop resorts to using his hypnotic powers against the Hulk, managing to brainwash him. Psyklop then sends the Hulk out to attack the inhabitants of K'ai who have begun to storm Psyklop's base. Unfortunately for Psyklop, the Hulk is returned to normal by several K'ai sorcerers and begins to advance on Psyklop. Taking Jarella hostage, Psyklop panics and begins trying to hypnotize the Hulk again, only to fail. Advancing on Psyklop, Hulk smashes the ground hard enough to break the urn in which Psyklop kept the spirits he captured. Before he can react, Psyklop is consumed by the spirits freed from the urn; all that remains of him is a pile of ash on the ground.