X-Factor is in Genosh and finds that most the mutates have contracted the Legacy Virus. Dr. Moira Mactaggert was in Genosha, tending to the handful of sick and dying, she was hoping against hope that it was strickly a mutate problem caused by their accelerated biologies.
The shapeshifting mutant and bodyguard to the Genoshan President, Piecemeal, makes his debut. Thats him on the cover with a hole in the middle.
Wolfsbane is emotionally distraught over what was done to her in Genosha and lashes out at Polaris and Moira.